Table 3.
Locoregional Recurrence | Distant Metastasis | ||||
---|---|---|---|---|---|
HR 95% CI | p | HR 95% CI | p | ||
Adjuvant Radiation | No vs Yes | 3.08 (0.72-13.27) | 0.131 | 0.21 (1.31-4.22) | 0.172 |
Tumor Size (cm) | 1.57 (1.18-2.09) | 0.002 | 2.35 (1.31-4.22) | 0.004 | |
Age at Diagnosis | 1.05 (1.01-1.09) | 0.027 | |||
Gender | Male vs Female | 3.04 (0.80-11.60) | 0.104 | 3.12 (0.91-10.65) | 0.069 |
CNI | No vs Yes | 0.19 (0.05-0.78) | 0.021 | ||
Positive Margin | No vs Yes | 0.42 (0.12-1.43) | 0.165 | ||
Bone Invasion | No vs Yes | 0.10 (0.01-1.04) | 0.054 | ||
Primary Site | Submandibular | 0.08 (0.01-0.94) | 0.045 | ||
Parotid | 0.07 (0.01-0.40) | 0.003 | |||
Sublingual | Reference | - | |||
Grade | Low/Intermediate vs High | 0.19(0.04-0.94) | 0.041 | ||
Degree of CNI | None | 0.09(0.02-0.32) | <0.001 | ||
Partial | 0.08(0.01-0.46) | 0.005 | |||
Complete | Reference | - | |||
T stage | T1/2 vs T3/4 | 6.81 (1.08-42.83) | 0.041 | ||
Histology | Adenocarcinoma | 7.14 (0.73-70.01) | 0.092 | ||
Acinic Cell | 1.89 (0.10-36.37) | 0.673 | |||
Adenoid Cystic | 9.09 (0.44-188.54) | 0.154 | |||
Mucoepidermoid | 0.41 (0.01-23.90) | 0.670 | |||
Other | Reference | - |
CM- centimeter, CNI-clinical nerve involvement. Bolded values denote statistical significance.