Table 4.

Multivariate Analysis by Prognostic Factors (Parotid Alone)

		Locoregional Recurrence		Distant Metastasis
		HR 95% CI	p	HR 95% CI	p
T Stage	T1/2 vs T3/4	0.05 (0.01-0.38)	0.004	4.23 (0.58-30.89)	0.156
Positive Margin	No vs Yes	0.32 (0.08-1.23)	0.098
Bone Invasion	No vs Yes	0.06 (0.00-1.04)	0.053
Adjuvant Radiation	No vs Yes	13.80 (2.11-90.47)	0.006
Degree of CNI	None vs Complete	0.06 (0.01-0.66)	0.021
	Partial vs Complete	0.18 (0.01-2.23)	0.182
Parotid Gland Location	Superficial vs Deep			0.08 (0.02-0.38)	0.001
Grade	Low/Intermediate vs High			0.15 (0.03-0.72)	0.018
PNI	No vs Yes	6.53 (0.74-57.58)	0.091	0.04 (0.01-0.29)	0.001
Age at Diagnosis		1.08 (1.02-1.13)	0.007	1.04 (0.99-1.08)	0.149

PNI-perineural invasion, T-tumor, CNI-clinical nerve involvement. Bolded values denote statistical significance.