Table 5.
Significant Prognostic Factors on Multivariate Analysis
| Institution (years) |
Number - sites |
Prognostic factors on Multivariate Analysis |
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T Stage |
N stage |
Stage | Grade | RT | Margin | Histology | CNI | Bone invasion |
Age | Gender | Subsite | PNI | Tumor size |
Deep parotid lobe |
RT | |||
| Terhaard[14] | Dutch (1985-94) | 565 – P, S, SL, M | LRR, DM, OS | LRR, DM, OS | LRR | DM | OS | OS | LRR | LRR, DM | ||||||||
| Mendenhall[12] | Florida (1964-2003) | 224 - P, S, SL, M | LRR | OS | LRR, DM, OS | LRR | ||||||||||||
| Garden[13] | MDACC (1961-1990) | 166 - P | OS | LRR | ||||||||||||||
| Chen[28] | UCSF (1960-2004) | 207 – P, S, SL | LRR | LRR | LRR | LRR | ||||||||||||
| Pohar[29] | SUNY/Kansas (1960-2000) | 163 -P | LRR | OS | LRR | LRR, OS | ||||||||||||
| Current | Emory (1997-2010) | 112 – P, S, SL | DM, LRR, OS | DM | LRR | LRR DM, OS | LRR | OS | DM | DM | LRR, DM | DM | LRR | |||||
DM – distant metastasis, LRR- locoregional recurrence, PFS – progression free survival, OS- overall survival, P-parotid, S- submandibular, SL-sublingual, CNI –clinical nerve involvement, PNI-perineural invasion