Table 4.
Prevalence (%) of DSM-IV mood, anxiety, and personality disorders, by pattern of polysubstance use among NESARC respondents with alcohol dependence at Wave 1
| Wave 1 diagnoses | Alcohol Use Only (n = 351) |
Alcohol and Tobacco Use (n = 402) |
Alcohol, Tobacco, and Cannabis Use (n = 171) |
Alcohol, Tobacco Cannabis, Cocaine and other Illicit Drug Use illicit drug(s) (n = 248) |
P-value | ||||
|---|---|---|---|---|---|---|---|---|---|
| % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | ||
| Mood and anxiety disorders (past-year): | |||||||||
| Major depressive episode | 14.94 | [10.9, 20.1] | 19.4 | [15.1, 24.6] | 20.6 | [13.9, 29.5] | 28.91 | [22.5, 36.3] | 0.0157 |
| Manic episode | 5.9 | [3.2, 10.7] | 5.8 | [3.7, 8.9] | 8.5 | [5.0, 14.0] | 10.9 | [7.1, 16.6] | 0.1661 |
| Panic disorder with/without agoraphobia | 3.14 | [1.7, 5.7] | 6.7 | [4.3, 10.4] | 7.2 | [3.7, 13.6] | 10.91 | [7.3, 16.1] | 0.0154 |
| Social phobia | 3.02,4 | [1.5, 5.7] | 9.61 | [6.4, 14.1] | 7.4 | [3.6, 14.7] | 9.01 | [5.6, 14.3] | 0.0307 |
| Specific phobia | 8.54 | [5.4, 13.2] | 14.6 | [10.9, 19.3] | 16.0 | [10.5, 23.5] | 20.21 | [14.5, 27.3] | 0.0269 |
| Generalized anxiety disorder | 3.4 | [1.5, 7.5] | 4.9 | [3.0, 8.0] | 5.4 | [2.8, 10.2] | 10.6 | [6.7, 16.5] | 0.0576 |
| Personality disorders (lifetime): | |||||||||
| Paranoid Personality Disorder | 9.04 | [5.7, 13.8] | 15.8 | [11.8, 20.7] | 14.7 | [9.4, 22.2] | 24.61 | [18.7, 31.8] | 0.0040 |
| Schizoid Personality Disorder | 6.0 | [3.8, 9.5] | 6.9 | [4.6, 10.3] | 7.7 | [3.8, 15.0] | 13.4 | [8.7, 20.0] | 0.0821 |
| Schizotypal Personality Disorder (Wave 2) | 5.54 | [3.2, 9.3] | 6.94 | [4.6, 10.2] | 10.4 | [5.8, 17.9] | 15.81,2 | [10.7, 22.6] | 0.0108 |
| Antisocial Personality Disorder (Wave 2) | 6.72,3,4 | [4.1, 10.7] | 17.91,4 | [13.8, 23.0] | 22.01 | [15.6, 30.2] | 33.01,2 | [26.7, 40.0] | <.0001 |
| Borderline Personality Disorder (Wave 2) | 11.23,4 | [7.8, 15.8] | 17.8 | [13.7, 22.8] | 27.81 | [20.4, 36.7] | 25.01 | [18.9, 32.3] | 0.0028 |
| Histrionic Personality Disorder | 8.84 | [5.8, 13.0] | 7.94 | [5.4, 11.5] | 8.9 | [5.0, 15.3] | 17.61,2 | [12.4, 24.4] | 0.0179 |
| Narcissistic Personality Disorder (Wave 2) | 11.53 | [8.0, 16.1] | 13.5 | [10.4, 17.4] | 22.91 | [16.0, 31.6] | 20.1 | [14.4, 27.2] | 0.0312 |
| Avoidant Personality Disorder | 4.8 | [3.0, 7.6] | 8.6 | [5.8, 12.5] | 8.1 | [4.2, 15.0] | 11.5 | [7.2, 17.9] | 0.0808 |
| Dependent Personality Disorder | 0.4 | [0.1, 2.2] | 1.8 | [0.8, 4.1] | 2.3 | [0.7, 7.0] | 5.0 | [2.3, 10.7] | 0.0595 |
| Obsessive-Compulsive Personality Disorder | 10.34 | [7.7, 13.7] | 16.5 | [12.5, 21.3] | 13.8 | [8.5, 21.6] | 21.21 | [15.5, 28.4] | 0.0197 |
Notes: The superscript i (i = 1, 2, 3, 4) indicates a significant pairwise comparison with the pattern i (Bonferroni adjusted p < 0.05). Personality disorders were diagnosed at Wave 1 unless otherwise noted.