Table 1.
SSI |
Time |
||||||||||||
T0 | T1 | T2 | T4 | T6 | T8 | T10 | T12 | T14 | T16 | T18 | T20 | ||
Group 1: PVA | Mean | -3.13 | -40.52 | -52.76 | -69.60 | -60.30 | -56.59 | -63.51 | -54.89 | -40.25 | -44.03 | -57.34 | -48.23 |
(n = 7) | SD | 24.17 | 19.25 | 17.78 | 9.56 | 19.69 | 13.19 | 8.05 | 11.96 | 13.33 | 9.07 | 21.81 | 7.25 |
Group 2: PVA-CNTs | Mean | 12.10 | -41.85 | -45.81 | -68.07 | -51.18 | -52.22 | -49.31 | -44.52 | -48.73 | -37.65 | -38.47 | -38.99 |
(n = 7) | SD | 34.10 | 20.82 | 23.21 | 17.00 | 11.41 | 41.96 | 21.11 | 17.62 | 26.31 | 20.78 | 17.97 | 31.11 |
Group 3: PVA-PPy | Mean | 5.31 | -41.40 | -50.95 | -45.76 | -47.40 | -34.56 | -39.51 | -31.52 | -32.47 | -43.17 | -50.00 | -36.08b |
(n = 7) | SD | 17.51 | 17.52 | 23.99 | 29.92 | 22.53 | 14.00 | 25.05 | 15.10 | 20.78 | 25.52 | 11.77 | 16.09 |
Group 4: Graft | Mean | -6.29 | -56.46 | -52.18 | -55.41 | -63.81 | -59.79 | -75.56 | -53.15 | -64.53 | -67.22 | -57.95 | -52.07 |
(n = 4) | SD | 1.59 | 28.10 | 27.54 | 27.99 | 19.06 | 11.00 | 10.45 | 15.44 | 12.14 | 12.17 | 8.31 | 9.76 |
Group 5: End-to-End | Mean | -5.78 | -44.21 | -33.72 | -58.28 | -73.92 | -70.22 | -52.47 | -68.04 | -41.91 | -46.56 | -43.04 | -59.97 |
(n = 5) | SD | 12.91 | 15.34 | 15.72 | 22.25 | 6.82 | 6.44 | 27.43 | 11.02 | 24.55 | 16.79 | 12.31 | 2.64 |
Group 6: PVA-CNTs-MSCs | Mean | 3.46 | -31.48 | -23.75 | -28.57 | -39.97 | -40.30 | -62.32 | -34.71 | -26.28 | -42.87 | -37.54 | -36.16b |
(n = 7) | SD | 12.35 | 21.89 | 19.70 | 9.96 | 9.20 | 21.72 | 18.07 | 16.44 | 15.31 | 25.75 | 10.06 | 14.87 |
Static sciatic functional index (SSI) measured pre-operatively (week-0), and every week after the surgical procedure until week-20. An index score of 0 is considered normal and an index of 100 indicates total impairment. The measurements of the toe spread (TS), and the intermediary TS, were taken from the experimental (E) and normal (N) sides. Results are presented as mean and SD. n corresponds to the number of rats within the experimental group. PVA: Polyvinyl alcohol; CNTs: Carbon nanotubes; PPy: Polypyrrole; MSCs: Mesenchymal stem cells.
P < 0.01 vs Graft.