Table 2.

AMSTAR rating table of included systematic reviews.

Reference	Year	A priori design?	Two data extractor and consensus?	Comprehensive literature search?	Statement on inclusion of grey literature? Language?	List of included and excluded studies?	Characteristics of studies provided, for example, tables?	Quality of risk of bias assessment?	Scientific quality of the included studies used appropriately in formulating conclusions?	Methods used to combine the findings of studies appropriate? Test on heterogeneity	Likelihood of publication bias assessed?	Conflict of interests stated?	Sum
CAM in general
Baranowsky et al. [50]	2009	Yes	Cannot answer	Yes	No	No	Yes	Yes	No	Not applicable	Not applicable	No	4
De Silva et al. [51]	2010	Yes	No	Yes	No	No	No	Yes	Yes	Not applicable	Not applicable	Yes	5
Holdcraft et al. [52]	2003	Yes	Cannot answer	Yes	No	No	No	Yes	Yes	Not applicable	Not applicable	No	4
Terhorst et al. [53]	2011	Yes	No	Yes	Yes	No	No	Yes	No	Yes	Yes	Yes	6
Exercise-based CAM
Chan et al. [54]	2012	Yes	No	Yes	No	No	Yes	Yes	Yes	Not applicable	Not applicable	Yes	6
Langhorst et al. [55]	2013	Yes	Yes	Yes	No	Yes	Yes	Yes	No	Yes	Yes	Yes	9
Lauche et al. [56]	2013	Yes	Yes	Yes	No	Yes	Yes	Yes	Yes	Yes	Yes	Yes	10
Mist et al. [57]	2013	Yes	Cannot answer	Yes	No	No	Yes	Yes	No	No	Yes	Yes	6
Manipulative therapies
Ernst [58]	2009	Yes	Yes	Yes	No	No	No	Yes	Yes	Not applicable	Not applicable	Yes	6
Kalichman [59]	2010	Cannot answer	Cannot answer	Yes	No	No	Yes	No	No	Not applicable	Not applicable	Yes	3
Schneider et al. [60]	2009	Yes	Cannot answer	Yes	Yes	No	No	Yes	No	Not applicable	Not applicable	Yes	5
Mind/Body interventions
Bernardy et al. [61]	2011	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	11
Glombiewski et al. [62]	2013	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes	Yes	10
Hadhazy et al. [63]	2000	Yes	Yes	Yes	Yes	No	Yes	Yes	Yes	Not applicable	Not applicable	No	7
Kozasa et al. [64]	2012	Cannot answer	Cannot answer	No	No	No	No	Yes	No	Not applicable	Not applicable	Yes	2
Lauche et al. [65]	2013	Yes	Yes	Yes	No	Yes	Yes	Yes	Yes	Yes	Yes	Yes	10
Acupuncture
Deare et al. [66]	2013	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	11
Langhorst et al. [67]	2010	Yes	Yes	Yes	Yes	No	Yes	Yes	Yes	Yes	No	Yes	9
Martin-Sanchez   et al. [68]	2009	Cannot answer	Cannot answer	Yes	No	No	No	No	No	Yes	No	Yes	3
Mayhew and   Ernst [69]	2007	Yes	Yes	Yes	No	No	No	Yes	No	Not applicable	Not applicable	Yes	5
Balneotherapy/hydrotherapy
Fraioli et al. [70]	2013	Cannot answer	Cannot answer	Yes	No	No	No	No	No	Not applicable	Not applicable	Yes	2
Langhorst et al. [71]	2009	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	11
McVeigh et al. [72]	2008	Yes	Yes	Yes	No	Yes	No	Yes	Yes	Not applicable	Not applicable	No	6
Phytotherapy
de Souza Nascimento et al. [73]	2013	Yes	Yes	Yes	No	No	Yes	Yes	Yes	Not applicable	Not applicable	Yes	7
Homeopathy
Perry et al. [74]	2010	Yes	Yes	Yes	No	No	No	Yes	Yes	Not applicable	Not applicable	Yes	5