Table 2.

Hepatic gene expression in male Wistar rats ¹.

		Diets
Symbol	Function	Control	11% PPC		p-Value
Srebf1	Transcription factor	1.00 ± 0.35	0.77 ± 0.08		0.189
Ppara	Transcription factor	1.00 ± 0.34	1.65 ± 1.06		0.262
Cd36/Fat	Fatty acid import	1.00 ± 0.23	1.27 ± 0.51		0.339
Cpt1a	β-oxidation	1.00 ± 0.33	2.07 ± 1.22		0.092
Cpt2	β-oxidation	1.00 ± 0.33	2.05 ± 1.19		0.118
Cact/Slc25a20	β-oxidation (transport)	1.00 ± 0.19	1.53 ± 0.68		0.162
Acox1	β-oxidation	1.00 ± 0.09	1.65 ± 0.44		0.017
Hmgcs2	Ketogenesis	1.00 ± 0.23	1.38 ± 0.70		0.320
Fasn	Fatty acid synthesis	1.00 ± 0.71	0.37 ± 0.26		0.103
Acaca	Fatty acid synthesis	1.00 ± 0.53	0.71 ± 0.23		0.298
Elo1	Fatty acid elongation	1.00 ± 0.10	1.06 ± 0.27		0.690
Scd1	Δ9 desaturation	1.00 ± 0.61	0.94 ± 0.59		0.890
Fads1	∆5 desaturation of fatty acids	1.00 ± 0.18	0.53 ± 0.22		0.011
Fads2	Δ6 desaturation of fatty acids	1.00 ± 0.25	0.62 ± 0.24		0.061
ApoB	Cholesterol import	1.00 ± 0.10	1.06 ± 0.20	0.617
Ldlr	Cholesterol import	1.00 ± 0.19	1.03 ± 0.37	0.898
Hmgcr	Cholesterol synthesis	1.00 ± 0.23	1.07± 0.19	0.636
Cyp7a1	Bile synthesis	1.00 ± 0.43	1.91 ± 1.64	0.304
Soat 1/Acat	Cholesterol ester formation	1.00 ± 0.14	0.98 ± 0.31	0.888
Gpam	TAG synthesis (glycerolipid synthesis)	1.00 ± 0.20	0.88 ± 0.18	0.386
Dgat	TAG synthesis	1.00 ± 0.17	1.24 ± 0.26	0.166
Mttp	Lipoprotein assembly	1.00 ± 0.11	1.20 ± 0.34	0.301
Lipc	Hepatisk lipase	1.00 ± 0.13	0.98 ± 0.22	0.850
Aadac	Triglycerid lipase activity	1.00 ± 0.11	1.20 ± 0.19	0.112
Sod2	Mitochondrial antioxidant defense system	1.00 ± 0.14	1.37 ± 0.26	0.038

PPC, phospholipid-protein complex. ¹ All values were normalized to Rplp0 and values relative to control are shown as means ± SD (n = 5 in control, n = 6 in 11% PPC). Results were analyzed by unpaired t-test, with significant p-values in bold (p ≤ 0.05). Abbreviations: Aadac, arylacetamide deacetylase; Acaca, acetyl-coA-carboxylase alpha; Acox1, acyl-CoA oxidase 1 palmitoyl; ApoB, apoprotein B; Cact/Slc25a20, carnitine-acylcarnitine translocase; Cd36/Fat, CD36 antigen/fatty acid translocase; Cpt1a, carnitine palmitoyltransferase 1A; Cpt2, carnitine palmitoyltransferase 2; Cyp7a1, cytochrome P450 family 7 subfamily A polypeptide 1; Dgat, diacylglycerol O-acyltransferase 1; Elo1, fatty acid elongase 1; Fads1, delta 5 desaturase/fatty acid desaturase 1; Fads2, delta 6 desaturase/fatty acid desaturase 2; Fasn, fatty acid synthase; Gpam, glycerol-3-phosphate acyltransferase mitochondrial; Hmgcr, 3-hydroxy-3-methylglutaryl-CoA reductase; Hmgcs2, 3-hydroxy-3-methylglutaryl-CoA synthase 2; Ldlr, low density lipoprotein receptor; Lipc, lipase hepatic; Mttp, microsomal triglyceride transfer protein; Ppara, peroxisome proliferator activated receptor alpha; Scd1, stearoyl-coenzyme A desaturase 1; Soat/Acat, sterol-O-acyltransferase 1/acyl-CoA:cholesterol acyltransferase; Sod2, superoxide dismutase 2, mitochondrial; Srebf1, sterol regulatory element binding transcription factor 1.