Skip to main content
. 2015 Jul 16;11(9):1088–1099. doi: 10.7150/ijbs.10603

Figure 1.

Figure 1

The effect of R-(-)-β-O-methylsynephrine on angiogenesis in fli1a:EGFP transgenic zebrafish embryos. Zebrafish embryos (n=30 per group) at the one-cell stage were used for the compound treatment. (A) Light microscopic images of whole embryos at 30 hours post fertilization (hpf) are shown. (B) Fluorescence images show dose-dependent suppression of intersegmental vessel (ISV) formation (indicated by arrows) by R-(-)-β-O-methylsynephrine (OMe-Syn). (C) Complete ISVs were counted at 30 hpf and quantified using Graphpad Prism software; **p<0.01 versus control (Student's t-test). (D) The viability of zebrafish embryos at 30 hpf upon treatment with OMe-Syn is shown.