Table 2.

Association tests of PNPLA3 single nucleotide polymorphisms

Groups	SNPs	Group (%)			OR (95%CI)			P value
		Normal	CHB	CHB + NAFLD	Unadjusted	Adjusted for age, sex	Adjusted for age, sex, and BMI	Unadjusted	Adjusted for age and sex	Adjusted for age, sex, and BMI
CHB+NAFLD vs CHB	738409		C: 57.84G: 42.16	C: 44.74G: 55.26	1.695(0.989-2.906)	2.334(1.169-4.657)	2.774(1.176-6.543)	0.054	0.016	0.020
	3747206		C: 57.84T: 42.16	C: 44.74T: 55.26	1.695(0.989-2.906)	2.334(1.169-4.657)	2.774(1.176-6.543)	0.054	0.016	0.020
	4823173		G: 58.82A: 41.18	G: 45.61A: 54.39	1.703(0.993-2.922)	2.134(1.089-4.180)	2.734(1.161-6.437)	0.052	0.027	0.021
	2072906		A: 58.82G: 41.18	C: 44.74G: 55.26	1.765 (1.028-3.029)	2.314(1.174-4.559)	3.045(1.277-7.262)	0.039	0.015	0.012
CHB+NAFLD vs normal	738409	C: 63.83G: 36.17		C: 44.74G: 55.26	2.180(1.246-3.815)	2.529(1.335-4.792)	3.018(1.318-6.914)	0.00	0.004	0.009
	3747206	C: 63.83G: 36.17		C: 44.74T: 55.26	2.180(1.246-3.815)	2.529(1.335-4.792)	3.018(1.318-6.914)	0.006	0.004	0.009
	4823173	C: 63.83G: 36.17		G: 45.61A: 54.39	2.104(1.203-3.681)	2.536(1.329-4.840)	3.212(1.344-7.679)	0.009	0.005	0.009
	2072906	C: 63.83G: 36.17		C: 44.74G: 55.26	2.180(1.246-3.815)	2.684(1.403-5.134)	3.499(1.452-8.430)	0.006	0.003	0.005
CHB vs normal	738409	C: 63.83G: 36.17	C: 57.84G: 42.16		1.286( 0.723-2.287)	1.356(0.695-2.643)	1.315(0.674-2.567)	0.391	0.372	0.422
	3747206	C: 63.83G: 36.17	C: 57.84T: 42.16		1.286(0.723-2.287)	1.356(0.695-2.643)	1.315(0.674-2.567)	0.391	0.372	0.422
	4823173	C: 63.83G: 36.17	G: 58.82A: 41.18		1.235(0.694-2.199)	1.439(0.717-2.889)	1.325(0.652-2.694)	0.472	0.306	0.437
	2072906	C: 63.83G: 36.17	G: 58.82A: 41.18		1.235(0.694-2.199)	1.439(0.717-2.889)	1.325(0.652-2.694)	0.472	0.306	0.437

BMI: Body mass index; CHB: Chronic hepatitis B; CI: Confidence interval; NAFLD: Nonalcoholic fatty liver disease; OR: Odds ratio; SNPs: Single nucleotide polymorphisms.