TABLE 6.
Adjusted ORs (95% CIs) of incident depression according to quintiles of specific nutrient density–adjusted foods1
| Incident depression 3 y later, OR (95% CI) |
||||
| Median | Incident depression after 3 y, n | Model 1 | Model 2 | |
| Fiber, g | ||||
| First quintile | 10.719 | 1154 | 1.00 | 1.00 |
| Second quintile | 13.725 | 982 | 0.84 (0.77, 0.92) | 0.96 (0.87, 1.06) |
| Third quintile | 16.061 | 930 | 0.79 (0.72, 0.87) | 0.97 (0.88, 1.08) |
| Fourth quintile | 18.306 | 817 | 0.69 (0.63, 0.76) | 0.91 (0.81, 1.01) |
| Fifth quintile | 21.136 | 760 | 0.64 (0.58, 0.70) | 0.86 (0.76, 0.98) |
| P-trend | <0.0001 | 0.0188 | ||
| Whole grains, oz | ||||
| First quintile | 0.251 | 1066 | 1.00 | 1.00 |
| Second quintile | 0.690 | 1025 | 0.96 (0.88, 1.05) | 1.04 (0.95, 1.15) |
| Third quintile | 1.069 | 904 | 0.84 (0.76, 0.92) | 0.96 (0.87, 1.06) |
| Fourth quintile | 1.474 | 836 | 0.77 (0.70, 0.85) | 0.93 (0.84, 1.03) |
| Fifth quintile | 2.293 | 812 | 0.75 (0.68, 0.82) | 0.92 (0.82, 1.02) |
| P-trend | <0.0001 | 0.0166 | ||
| Nonwhole/refined grains, oz | ||||
| First quintile | 1.720 | 858 | 1.00 | 1.00 |
| Second quintile | 2.627 | 826 | 0.96 (0.87, 1.06) | 0.94 (0.85, 1.04) |
| Third quintile | 3.277 | 964 | 1.13 (1.03, 1.25) | 1.07 (0.97, 1.18) |
| Fourth quintile | 3.946 | 962 | 1.13 (1.03, 1.24) | 1.04 (0.94, 1.15) |
| Fifth quintile | 5.271 | 1033 | 1.22 (1.11, 1.34) | 1.12 (1.01, 1.24) |
| P-trend | <0.0001 | 0.0072 | ||
| Nonjuice fruit, cups | ||||
| First quintile | 0.248 | 1198 | 1.00 | 1.00 |
| Second quintile | 0.667 | 954 | 0.78 (0.71, 0.85) | 0.92 (0.84, 1.01) |
| Third quintile | 0.885 | 876 | 0.70 (0.64, 0.76) | 0.88 (0.80, 0.97) |
| Fourth quintile | 1.647 | 840 | 0.65 (0.59, 0.71) | 0.88 (0.79, 0.98) |
| Fifth quintile | 2.338 | 775 | 0.63 (0.58, 0.70) | 0.88 (0.79, 0.99) |
| P-trend | <0.0001 | 0.0247 | ||
| Vegetables, medium portion | ||||
| First quintile | 0.997 | 1222 | 1.00 | 1.00 |
| Second quintile | 1.603 | 975 | 0.78 (0.72, 0.85) | 0.93 (0.84, 1.02) |
| Third quintile | 2.132 | 851 | 0.68 (0.62, 0.74) | 0.88 (0.79, 0.97) |
| Fourth quintile | 2.778 | 803 | 0.64 (0.58, 0.70) | 0.86 (0.78, 0.96) |
| Fifth quintile | 3.753 | 792 | 0.62 (0.57, 0.69) | 0.88 (0.79, 0.99) |
| P-trend | <0.0001 | 0.0128 | ||
| Nuts/seeds, oz | ||||
| First quintile | 0.000 | 1019 | 1.00 | 1.00 |
| Second quintile | 0.066 | 958 | 0.95 (0.87, 1.04) | 0.93 (0.85, 1.03) |
| Third quintile | 0.154 | 840 | 0.82 (0.75, 0.90) | 0.83 (0.75, 0.91) |
| Fourth quintile | 0.285 | 907 | 0.90 (0.81, 0.98) | 0.93 (0.85, 1.03) |
| Fifth quintile | 0.987 | 919 | 0.90 (0.82, 0.99) | 0.92 (0.83, 1.02) |
| P-trend | 0.0097 | 0.1530 | ||
| Legumes, cups | ||||
| First quintile | 0.003 | 948 | 1.00 | 1.00 |
| Second quintile | 0.030 | 981 | 0.91 (0.83, 1.01) | 1.03 (0.94, 1.13) |
| Third quintile | 0.057 | 913 | 0.99 (0.89, 1.10) | 0.97 (0.88, 1.07) |
| Fourth quintile | 0.097 | 853 | 0.98 (0.88, 1.09) | 0.91 (0.82, 1.01) |
| Fifth quintile | 0.203 | 948 | 1.02 (0.91, 1.15) | 0.99 (0.86, 1.09) |
| P-trend | 0.1607 | 0.2004 | ||
Model 1 was nutrient density adjusted; model 2 adjusted for variables in model 1 plus race-ethnicity, education, income, BMI, diabetes, hypertension, hormone replacement therapy, stroke, myocardial infarction, Alzheimer disease, cardiovascular disease, cancer, physical activity, stressful life events, social support, smoking, alcohol, and energy-adjusted intakes of SFAs, MUFAs, PUFAs, and trans fatty acids. One cup = 236.588 mL. oz, ounces (1 oz = 28.3495 g).