. 2015 Jul 28;13:245. doi: 10.1186/s12967-015-0598-6

Table 5.

Effect on antioxidant enzymes and GSH levels in liver, kidney, heart, brain and testes in absence (CdCl₂) and presence of AEIA (AEIA + CdCl₂) and AEEF (AEEF + CdCl₂) in mice

Parameters	Group	Liver	Kidney	Heart	Brain	Testes
CAT (U/mg of protein)	I	312.92 ± 27.65	248.22 ± 21.24	313.24 ± 21.33	94.12 ± 6.67	41.25 ± 3.87
	II	178.43 ± 16.86^#	128.30 ± 14.04^#	192.56 ± 17.04^#	46.45 ± 3.92^#	25.54 ± 3.01^$
	III	279.88 ± 25.46**	221.33 ± 23.78**	267.54 ± 16.92*	69.75 ± 6.78*	38.76 ± 2.98*
	IV	264.20 ± 27.11*	214.34 ± 17.67*	261.41 ± 18.00*	67.22 ± 5.98	35.43 ± 3.93
SOD (U/mg of protein)	I	82.17 ± 7.21	78.02 ± 6.89	134.69 ± 10.17	94.52 ± 6.25	119.42 ± 8.13
	II	45.83 ± 4.34^#	42.34 ± 4.71^#	78.35 ± 8.92^#	52.24 ± 5.08^#	78.34 ± 7.78^$
	III	76.51 ± 6.94**	72.86 ± 6.94**	119.85 ± 11.01*	78.92 ± 7.38*	111.85 ± 9.25*
	IV	75.33 ± 6.23**	69.87 ± 7.18*	119.61 ± 9.87*	73.05 ± 7.01	103.61 ± 9.96
GST (µmol/h/mg protein)	I	1.28 ± 0.18	1.34 ± 0.11	0.64 ± 0.06	1.75 ± 0.15	4.51 ± 0.36
	II	0.59 ± 0.07^#	0.68 ± 0.05^#	0.42 ± 0.03^#	1.24 ± 0.09^$	2.45 ± 0.21^#
	III	1.16 ± 0.14*	1.21 ± 0.10**	0.61 ± 0.04*	1.67 ± 0.09*	3.91 ± 0.40*
	IV	1.14 ± 0.09*	1.20 ± 0.08*	0.59 ± 0.05*	1.65 ± 0.12	3.78 ± 0.33*
GPx (nmol/min/mg protein)	I	123.85 ± 6.67	43.62 ± 3.78	312.15 ± 16.33	165.43 ± 8.94	162.05 ± 7.65
	II	78.50 ± 4.42^#	26.95 ± 2.21^#	206.96 ± 12.28^#	121.35 ± 6.67^#	112.33 ± 6.10^#
	III	108.50 ± 5.33**	39.28 ± 2.89*	278.36 ± 17.82*	155.85 ± 8.12*	148.76 ± 6.05**
	IV	102.05 ± 5.12*	38.47 ± 3.01*	272.84 ± 14.95*	148.33 ± 7.33	142.50 ± 7.02*
GR (nmol/min/mg protein)	I	88.85 ± 6.33	34.51 ± 2.87	82.17 ± 4.01	48.12 ± 4.49	85.10 ± 4.54
	II	61.78 ± 4.18^#	19.33 ± 2.02^#	42.76 ± 2.19^#	28.94 ± 2.86^#	52.95 ± 4.20^#
	III	84.33 ± 8.02*	31.24 ± 2.49**	63.21 ± 3.77**	40.70 ± 3.55	69.43 ± 3.36*
	IV	77.36 ± 5.79	29.72 ± 1.92*	58.76 ± 3.54*	38.29 ± 3.02	63.21 ± 4.47
G6PD (nmol/min/mg protein)	I	104.32 ± 9.12	86.74 ± 7.12	98.32 ± 5.14	34.68 ± 3.06	54.25 ± 4.72
	II	54.31 ± 5.76^#	45.17 ± 3.22^#	69.28 ± 4.21^#	19.43 ± 2.33^#	34.56 ± 2.89^#
	III	86.08 ± 7.11*	72.16 ± 5.15**	89.67 ± 4.75*	26.54 ± 1.76	46.29 ± 3.16
	IV	85.33 ± 6.58*	67.21 ± 4.99*	86.23 ± 4.77	25.33 ± 1.58	45.02 ± 3.04
GSH (nmol/mg protein)	I	24.21 ± 2.54	16.54 ± 1.01	19.51 ± 2.01	27.12 ± 2.67	17.65 ± 1.87
	II	13.21 ± 1.69^#	8.33 ± 0.82^#	9.34 ± 1.54^#	13.25 ± 1.48^#	9.67 ± 1.00^#
	III	21.88 ± 2.05*	13.45 ± 1.15**	15.43 ± 1.67*	18.24 ± 1.92*	15.67 ± 1.24*
	IV	21.35 ± 1.90*	12.67 ± 0.98*	14.45 ± 1.48	19.12 ± 1.78	15.02 ± 1.61*

Values are expressed as mean ± SE, for six animals in each group. ^#Values differ significantly from normal control (p < 0.01). ^$ Values differ significantly from normal control (p < 0.05). * Values differ significantly from CdCl₂ control (p < 0.05). ** Values differ significantly from CdCl₂ control (p < 0.01). Group I: Normal control; Group II: Toxic control; Group III: AEIA (100 mg/kg) + CdCl₂ (4 mg/kg); Group IV: AEEF (100 mg/kg) + CdCl₂ (4 mg/kg).