Figure 10.

Longitudinal time-series Model I, symptomatic versus control with a view of the significant vertices as measured by log-Jacobian change between control and symptomatic group. Significant vertices showing consistent local volume decreases as determined by the FWER at 5% linear effects Model I; blue vertices represent vertices which are not significant. Color codes percentage decrease of surface area from control to symptomatic, with color given by $-\left(\mathrm{\beta }\text{+}{\mathrm{\beta }}_v^{\prime }\overline{\text{age}}\right)$, with $\overline{\text{age}}$ the average age of the symptomatic group. Structures placed into coordinates of one brain depicting the relative relationships of the most significant changes in color from blue to red. Maximum changes of relative surface area of symptomatic population to control population are 21% for ERC; the maximum for hippocampus is 15.5%, and 15% for amygdala; all significant change (non-blue) is atrophy. Sulcal region denoting the most lateral portion of ERC is depicted.