Table 4.
Potential risk factors for PD at baseline and 6 months after SAH
| Clinical characteristics | Baseline | 6 months’ follow-up | ||
|---|---|---|---|---|
| With PD N=37 |
Without PD N=47 |
With PD N=22 |
Without PD N=62 |
|
| Age; mean (SD) | 57.5 (11.9) | 54.3 (11.8) | 52.9 (12.0) | 56.7 (11.8) |
| Male | 10 (27%) | 18 (38%) | 10 (45%) | 18 (29%) |
| Days in hospital; mean (SD) | 18.4 (8.1) | 18.0 (10.9) | 19.7 (9.1) | 17.7 (9.9) |
| History of smoking | 23 (62%) | 29 (62%) | 14 (64%) | 38 (61%) |
| History of hypertension | 11 (30%) | 7 (15%) | 6 (27%) | 12 (19%) |
| History of DM | 0 | 4 (9%) | 0 | 4 (6%) |
| History of hypercholesterolaemia | 8 (22%) | 7 (15%) | 2 (9%) | 13 (21%) |
| BMI; mean (SD) | 25.5 (4.1) | 25.1 (3.4) | 25.2 (3.6) | 25.3 (3.8) |
| GCS on admission | * | |||
| 13–15 | 27 (73%) | 39 (83%) | 14 (64%) | 52 (84%) |
| 9–12 | 5 (13.5%) | 6 (13%) | 4 (18%) | 7 (11%) |
| 3–8 | 5 (13.5%) | 2 (4%) | 4 (18%) | 3 (5%) |
| WFNS on admission | * | |||
| Grade I | 14 (38%) | 24 (51%) | 8 (36%) | 31 (50%) |
| Grade II | 11 (30%) | 14 (30%) | 5 (23%) | 20 (32%) |
| Grade III | 2 (5%) | 1 (2%) | 1 (5%) | 2 (3%) |
| Grade IV | 5 (13.5%) | 6 (13%) | 4 (18%) | 7 (11%) |
| Grade V | 5 (13.5%) | 2 (4%) | 4 (18%) | 3 (5%) |
| Location of aneurysm | ||||
| Anterior circulation | 17 (46%) | 31 (66%) | 12 (55%) | 37 (60%) |
| Posterior circulation | 20 (54%) | 16 (34%) | 10 (45%) | 25 (40%) |
| SAH treatment | ||||
| Coiling | 30 (81%) | 36 (77%) | 19 (86%) | 47 (76%) |
| Clipping | 6 (19%) | 11 (23%) | 2 (9%) | 15 (24%) |
| Complications | ‡ | |||
| Any | 23 (62%) | 18 (38%) | 14 (64%) | 27 (44%) |
| Hydrocephalus | 18 (49%) | 13 (28%) | 13 (59%)† | 18 (29%) |
| Delayed Cerebral Ischaemia | 7 (19%) | 7 (15%) | 3 (14%) | 11 (18%) |
| Rebleed | 1 (3%) | 1 (2%) | 0 | 2 (3%) |
| ICH | 5 (13.5%) | 10 (21%) | 3 (14%) | 12 (19%) |
| IVH | 26 (70%) | 30 (64%) | 13 (59%) | 43 (69%) |
| Hypertension after SAH | 20 (54%) | 29 (62%) | 14 (64%)* | 22 (35%) |
*p<0.05.
†OR 3.3 (95% CI 2.7 to 3.8).
‡OR 2.6 (95% CI 2.2 to 3.0).
BMI, body mass index; GCS, Glasgow Coma Scale; ICH, intraparenchymal haematoma; IVH, intraventricular haematoma; PD, pituitary dysfunction; SAH, subarachnoid haemorrhage. WFNS, World Federation of Neurological Surgeons grading scale for patients with SAH.