Table 3.
Per-patient per-year health care utilization and costsa
| Measure
|
Non-metastatic, post-surgery melanoma cohort
|
Ratio IFN treatment/non-IFN treatment b | P-value for mean cost | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients with IFN therapy following index surgery (N=179)
|
Patients without IFN following index surgery (N=1,820)
|
|||||||||||
| Resource | N | Mean | SD | IQR | Median | N | Mean | SD | IQR | Median | ||
| Index surgery | ||||||||||||
| Anesthesia | 172 | $1,014 | $640 | $458 | $869 | 1,733 | $679 | $444 | $379 | $613 | 1.49 | <0.0001 |
| Surgery | 179 | $2,030 | $1,079 | $777 | $1,740 | 1,818 | $1,419 | $742 | $677 | $1,249 | 1.43 | <0.0001 |
| Pathology | 174 | $370 | $198 | $155 | $330 | 1,740 | $400 | $239 | $180 | $362 | 0.93 | |
| Hospital care | 36 | $454 | $274 | $372 | $372 | $229 | $433 | $311 | $309 | $329 | 1.05 | |
| Follow-up surgery/surgeries | ||||||||||||
| Anesthesia | 80 | $762 | $409 | $360 | $663 | 672 | $636 | $376 | $362 | $592 | 1.20 | 0.0054 |
| Surgery | 7 | $1,688 | $1,051 | $1,552 | $1,380 | 77 | $2,032 | $2,751 | $1,457 | $1,195 | 0.83 | |
| Pathology | 130 | $376 | $107 | $88 | $359 | 1,219 | $321 | $98 | $99 | $310 | 1.17 | <0.0001 |
| Hospital care | 56 | $490 | $252 | $243 | $430 | 418 | $549 | $268 | $300 | $497 | 0.89 | |
| Melanoma-related medical services | ||||||||||||
| Outpatient services | 178 | $32,414 | $2,498 | $3,490 | $32,200 | 1,791 | $10,556 | $1,128 | $1,504 | $10,444 | 3.07 | <0.0001 |
| Office visits | 177 | $1,995 | $709 | $697 | $1,824 | 1,771 | $1,048 | $409 | $358 | $972 | 1.90 | <0.0001 |
| Outpatient laboratory | 165 | $277 | $136 | $167 | $248 | 1,163 | $79 | $42 | $47 | $72 | 3.50 | <0.0001 |
| Impatient services | 80 | $10,868 | $4,716 | $5,369 | $10,798 | 448 | $11,358 | $6,241 | $8,554 | $10,626 | 0.96 | |
| Radiation therapy | 33 | $7,627 | $5,006 | $4,406 | $5,948 | 148 | $8,360 | $5,836 | $6,836 | $6,681 | 0.91 | |
| Total cost | ||||||||||||
| Melanoma-related medical | 178 | $38,730 | $4,254 | $2,679 | $39,140 | 1,797 | $13,995 | $2,676 | $5,411 | $15,276 | 2.77 | <0.0001 |
| Non-melanoma-related medical | 179 | $22,415 | $12,668 | $10,204 | $19,026 | 1,811 | $18,442 | $13,438 | $7,753 | $15,416 | 1.22 | <0.0001 |
| Overall total cost | 179 | $60,755 | $3,972 | $7,283 | $58,968 | 1,818 | $31,641 | $2,471 | $6,182 | $31,214 | 1.92 | <0.0001 |
Notes:
a
Adjusted for age index date (group), insurance type at index date, region, sex, specialty at index date, year of diagnosis, year of index, listed comorbidities, and listed chemotherapy;
b
ratio IFN treatment/non-IFN treatment was based on mean values. Costs reported in 2012 USD.
Abbreviations: SD, standard deviation; IQR, interquartile range.