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BAF and PBAF complexes. The subunits specific to the BAF complex including ARID1A and ARID1B and to the PBAF complex including ARID2 and PBRM1 are demonstrated in the cartoon rendition of the complexes. Mutations in subunits colored in blue have been demonstrated in the literature to be associated with cancer, and subunits with mutations that have been associated with either cancer and/or known genetic disorders (i.e. Coffin-Siris syndrome) are colored in purple.
