Table 1.
Characteristics of patients enrolled in stomach biopsy cohort. First two years of follow-up are excluded
| Mucosal status at baseline* | No of participants | Mean (SD) age at entry (years)† | % male | Mean (SD) follow-up (years) | Accumulated person years† |
|---|---|---|---|---|---|
| Correa’s cascade: | |||||
| Normal | 81 174 | 47.7 (19.9) | 40.5 | 9.7 (5.7) | 621 359 |
| Minor mucosal change | 11 571 | 57.5 (18.5) | 43.8 | 10.2 (6.6) | 95 437 |
| Gastritis | 167 521 | 58.3 (18.2) | 46.5 | 10.7 (6.2) | 1 463 788 |
| Atrophic gastritis | 14 285 | 60.3 (18.5) | 41.3 | 10.1 (6.3) | 115 583 |
| Intestinal metaplasia | 11 530 | 66.1 (14.7) | 47.8 | 7.9 (4.6) | 68 122 |
| Dysplasia | 2086 | 65.5 (14.9) | 51.3 | 10.0 (6.0) | 16 743 |
| Overall | 288 167 | 55.7 (19.3) | 44.5 | 10.3 (6.1) | 2 381 032 |
| Other diagnoses: | |||||
| Cellular degeneration/infiltration or abnormal karyotype | 826 | 60.1 (18.8) | 50.9 | 9.4 (5.7) | 6120 |
| Reactive gastropathy | 9130 | 53.2 (17.5) | 37.3 | 5.9 (2.9) | 35 699 |
| Atypia | 5124 | 63.9 (14.5) | 54.3 | 11.4 (6.8) | 48 254 |
| Hyperplasia or hypertrophy | 12 392 | 60.9 (16.5) | 40.8 | 9.1 (5.3) | 87 853 |
| Metaplasia (not intestinal metaplasia) | 9883 | 65.2 (14.7) | 49.4 | 10.3 (5.7) | 82 399 |
| Polyps | 13 935 | 61.7 (14.3) | 36.3 | 9.3 (5.5) | 101 289 |
| Benign tumour | 2840 | 62.3 (16.1) | 35.2 | 9.0 (5.6) | 19 989 |
| Overall | 54 130 | 60.9 (16.1) | 41.8 | 9.0 (5.5) | 381 603 |
*Defined as first biopsy identified in database. When multiple diagnoses were present, the most severe one was selected.
†Calculated after exclusion of first two years of follow-up.