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. 2015 Jul 20;8:1785–1794. doi: 10.2147/OTT.S85383

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© 2015 Yao et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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MTA1 promotes migration and invasion of human gastric cancer cells.

Notes: Transwell cell migration (A) and invasion (B) assays of SGC7901 and BGC823 cells stably expressing control (Ctrl) vector and MTA1. Representative photomicrographs of Transwell results were taken under ×200 magnification. Scale bars: 200 µm. The average number of migrated cells is shown. Statistical significance compared to gastric cancer cells was calculated using Student’s t-test. Bar charts show mean (± standard deviation) values from three independent experiments. **P<0.01. In SGC7901 (C) and BGC823 (D) cells, overexpression of MTA1 and Ctrl cells were collected and indicated proteins were detected using Western blot.

Abbreviations: Ctrl, control; MTA1, metastasis-associated protein 1.