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. 2015 Jul 21;9:3779–3787. doi: 10.2147/DDDT.S83047

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© 2015 Revathi et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Antitubercular activity of compounds PB1–PB20.

Notes: A: pyrazinamide. B: ethambutol. C: isoniazid. PB1: 1-(1H-benzimidazol-2-ylmethyl)piperidin-4-one. PB2: 1-(1H-benzimidazol-2-ylmethyl)-N-hydroxypiperidin-4-imine. PB3: 2-[(4-hydrazinylidenepiperidin-1-yl)methyl]-1H-benzimidazole. PB4: 2-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]hydrazinecarbothioamide. PB5: 2-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]-N-hydroxyhydrazinecarbo-thioamide. PB6: N-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]-4-fluoroaniline. PB7: 2-{[4-(2-phenylhydrazinylidene)piperidin-1-yl]methyl}-1H-benzimidazole. PB8: N-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]-2,4-dimethoxyaniline. PB9: N-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]-2,3-dimethylaniline. PB10: N-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]-3-chloro-2-methylaniline. PB11: N-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]-2,4-dichloroaniline. PB12: N-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]-2,4-difluoroaniline. PB13: 1-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]guanidine. PB14: N-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]aniline. PB15: N-[1-(1H-benzimidazol-2-ylmethyl) piperidin-4-ylidene]-4-chloroaniline. PB16: 1-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]urea. PB17: N-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]-2,4-dinitroaniline. PB18: 1-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]thiourea. PB19: 1-(1H-benzimidazol-2-ylmethyl)-N-methoxypiperidin-4-imine. PB20: 2-[1-(1H-benzimidazol-2-ylmethyl)piperidin-4-ylidene]hydrazinecarboxamide.

Abbreviation: MIC, minimum inhibitory concentration.