Figure 1.

Targets of antithrombotic and antiplatelet agents including vorapaxar (SCH 530348).

Note: Reproduced with permission from Angiolillo DJ, Capodanno D, Goto S. Platelet thrombin receptor antagonism and atherothrombosis, Eur Heart J. 2010;31(1):17–28. By permission of Oxford University Press.19

Abbreviations: ADP, adenosine diphosphate; COX, cyclo-oxygenase; vWF, von Willebrand factor; PAR, protease-activated receptor; TxA₂, thromboxane A₂.