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. Author manuscript; available in PMC: 2015 Jul 27.
Published in final edited form as: Arthritis Rheumatol. 2014 Jan;66(1):203–212. doi: 10.1002/art.38191

Figure 5. Direct searches in the ventral tegmental area.

Figure 5

The VTA mask for the ROI analyses (left) was drawn in the midbrain, medial to the substantia nigra and ventral to the red nucleus (right; adapted from the Duvernoy's atlas (24)) (A). In FM, VTA responses to anticipation of pain, pain and anticipation of relief were statistically reduced, compared to controls. Bars represent mean ± SEM (B). VTA responses to pain anticipation and relief anticipation were negatively correlated in healthy controls, but not in FM patients (C).