Table III. Recent Developments on the Hydrogel Based Formulations.
| Drug | Polymer | Mechanism of gelation | Ref |
|---|---|---|---|
| Pefloxacin mesylate | Gelrite gellan gum | Ion | (219) |
| Gatifloxacin | Alginate and HPMC | Ion | (220) |
| Indomethacin | Gelrite (gellan gum) | Ion | (221) |
| Ciprofloxacin HCL | Gelrite gellan gum and sodium alginate | Ion | (222) |
| Gatifloxacin | Ion | (223) | |
| Timolol maleate | Gellan gum | Ion | (224) |
| Ofloxacin | Carbopol 940 and HPMC | pH | (225) |
| Puerarin | Carbopol/HPMC-based gel | pH | (226) |
| Puerarin | Poloxamer analogs/carbopol | pH | (227) |
| Fluconazole | In-situ gelling eye drops | – | (228) |
| Ganciclovir | In-situ gelling eye drops | – | (229) |
| Timolol maleate | Pluronic F127 | Temperature | (148) |
| Timolol maleate | poly(Nisopropylacrylamide)-chitosan | Temperature | (230) |
| Pilocarpine | Alginate and pluronic-based in situ gelling | Ion and temperature | (231) |
| Timolol maleate | Pluronic F-127 and chitosan | pH and temperature | (232) |
| Gatifloxacin | Pluronic F127-g-poly(acrylic acid) copolymers | pH and temperature | (233) |
| Pilocarpine | Xyloglucan | Temperature | (150) |