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. Author manuscript; available in PMC: 2015 Jul 27.
Published in final edited form as: Int J Parasitol. 2014 Apr 12;44(7):485–496. doi: 10.1016/j.ijpara.2014.03.005

Fig. 3.

Fig. 3

A rooted neighbour joining tree showing the relationships of Haemonchus contortus insulin-like receptor Hc-DAF-2 to the insulin-like receptors of nine nematodes and nine non-nematodes. The tree was calculated using the Jones-Taylor-Thornton model in the MEGA program version 5.0. Bootstrap values above or below the branches (1000 iterations) are shown for robust clades (>50%). These 18 species include nine nematodes (Brugia malayi, Bm-DAF-2; Loa loa, Ll-DAF-2; Ascaris suum, As-DAF-2; Caenorhabditis elegans, Ce-DAF-2; Caenorhabditis briggsae, Cb-DAF-2; Parastrongyloides trichosuri, Pt-DAF-2; Strongyloides stercoralis, Ss-DAF-2A and Ss-DAF-2B; Trichinella spiralis, Ts-DAF-2), Molluscs (Lymnaea stagnalis, LsIR; Biomphalaria glabrata, BgIR), Insects (Aedes aegypti, AaIR; Drosophila melanogaster, DmIR; Bombyx mori, BmoIR), Vertebrates (Xenopus laevis, XlIR; Homo sapiens, HsIR; Homo sapiens, HsIGF1R; Mus musculus, MmIGF1R). Their corresponding accession numbers are listed on the right of each species. Mus musculus EGFR (MmEGFR) was used as the outgroup.