Table 1. Characteristics of the 790 patients with urinary tract infection.
| Characteristic | All (n = 790) | Acute kidney injury | P-Value | |
|---|---|---|---|---|
| Yes (n = 97) | No (n = 693) | |||
| Age (year) | 65 ± 18 | 72 ± 13 | 64 ± 19 | <0.001 |
| Gender (female) | 543 (68.7) | 72 (74.2) | 471 (68.0) | 0.213 |
| Systolic blood pressure (mmHg) | 135 ± 30 | 127 ± 33 | 137 ± 30 | 0.006 |
| Diastolic blood pressure (mmHg) | 75.82 ± 15.8 | 70 ± 17 | 77 ± 15 | <0.001 |
| Diabetes mellitus | 302 (38.2) | 55 (56.7) | 247 (35.6) | <0.001 |
| Hypertension | 335 (42.4) | 53 (54.6) | 282 (40.7) | 0.009 |
| Congestive heart failure | 29 (3.7) | 5 (5.2) | 24 (3.5) | 0.387 |
| Coronary artery disease | 55 (7.0) | 10 (10.3) | 45 (6.5) | 0.167 |
| Stroke | 178 (22.5) | 21 (21.6) | 157 (22.7) | 0.824 |
| Malignancy | 92 (11.6) | 16 (16.5) | 76 (11.0) | 0.112 |
| Indwelling foley catheter | 54 (6.8) | 8 (8.2) | 46 (6.6) | 0.556 |
| Afebrile | 369 (46.7) | 58 (59.8) | 311 (44.9) | 0.006 |
| Upper urinary tract infection | 291 (36.8) | 45 (46.4) | 246 (35.5) | 0.037 |
| Bacteremia | 236 (29.9) | 38 (39.2) | 198 (28.6) | 0.033 |
| Septic shock | 90 (11.4) | 22 (22.7) | 68 (9.8) | <0.001 |
| Hospitalized serum creatinine (mg/dL) | 1.57 ± 1.30 | 3.37 ± 1.96 | 1.32 ± 0.94 | <0.001 |
| Baseline eGFR (mL/min/1.73 m2) | 70 ± 28 | 53 ± 23 | 72 ± 27 | <0.001 |
| Baseline renal function (eGFR) | <0.001 | |||
| ≥ 60 mL/min/1.73m2 | 497 (62.9) | 32 (33.0) | 465 (67.1) | |
| 45–59 mL/min/1.73m2 | 132 (16.7) | 23 (23.7) | 109 (15.7) | |
| 30–44 mL/min/1.73m2 | 103 (13.0) | 27 (27.8) | 76 (11.0) | |
| < 30 mL/min/1.73m2 | 58 (7.3) | 15 (15.5) | 43 (6.2) | |
| Nephrotoxic agents | 526 (66.6) | 46 (47.4) | 480 (69.3) | <0.001 |
| Aminoglycosides | 290 (36.8) | 16 (16.3) | 274 (39.7) | <0.001 |
| Nonsteroidal anti-inflammatory drugs | 392 (49.6) | 36 (36.7) | 356 (51.4) | 0.006 |
| Contrast media | 99 (12.5) | 16 (16.3) | 83 (12.0) | 0.225 |
| Trimethoprim/sulfamethoxazole | 21 (2.7) | 4 (4.1) | 17 (2.5) | 0.317 |
| Antihypertensive agents | 429 (54.3) | 66 (68.0) | 363 (52.4) | 0.004 |
Data are expressed as mean ± SD or number (percentage)