TABLE 2.
Distribution of OAA-synthesizing enzymes in archaeaa
| Organism (reference for experimental and genome sequence data)b | ORF no. or absence of ORFc
|
||
|---|---|---|---|
| PpcA | PYCA/PYCBd | PCKe | |
| Methanogens | |||
| Methanocaldococcus jannaschii (4, 39) | Absent | MJ1229/MJ1231 | Absent |
| Methanococcus maripaludis (50) (BX950229)f | Absent | MMP0341/MMP0340 | Absent |
| Methanopyrus kandleri (20, 53) | MK0190 | Absent | Absent |
| Methanothermobacter thermautotrophicus (14, 31, 42, 54) | MTH943 | MTH1917/MTH1107 | Absent |
| Methanosarcina barkeri (41) | METH1932 | METH3573/METH3572 | Absenth |
| Methanosarcina mazei (9) | MM3212 | MM1828/MM1827 | Absent |
| Methanosarcina acetivorans (18) | MA2690 | MA0675/MA0674 | Absent |
| Methanococcoides burtonii (48) | Absenth | Mbur125601/Mbur125501 | Absenth |
| Nonmethanogens | |||
| Halobacterium sp. NRC-1 (43) | VNG2259c | Absent | Absent |
| Archaeoglobus fulgidus (32) | AF1486 | Absent | Absent |
| Pyrococcus furiosus (45) | PF1975 | Absent | PF0289 |
| Pyrococcus horikoshii (28) | PH0016 | Absent | PH0312 |
| Pyrococcus abyssi (8) | PAB2342 | Absent | PAB1253 |
| Thermoplasma acidophilum (46) | Absent | Absent | Ta0123 |
| Thermoplasma volcanium (29) | Absent | Absent | TVN0200 |
| Ferroplasma acidarmanus | FACI0253 | Absenth | FACI0139 |
| Pyrobaculum aerophilum (13) | PAE3416 | Absent | Absent |
| Sulfolobus acidocaldarius (47a) | Present | —i | — |
| Sulfolobus solfataricus (49) | SSO2256 | Absent | SSO2537 |
| Sulfolobus tokadaii (26) | ST2101 | Absent | ST1058 |
| Aeropyrum pernix (27) | Absent | Absent | APE0033g |
The evidence for PpcA in M. thermautotrophicus and PYCA and PYCB in M. jannaschii, M. thermautotrophicus, and M. barkeri are experimental (31, 39, 41, 42; this work); M. maripaludis and S. acidocaldarius data are partly experimental (47a, 50). The rest of the data were inferred from the sequence data in the National Center for Biotechnology Information database.
Organisms in bold are Crenarchaea; all other organisms are Euryarchaea.
Retrieved from the National Center for Biotechnology Information database from similarity searches by use of MTH943 (for PpcA), M. thermautotrophicus PYC subunits (for PYCA and PYCB) (42), E. coli PCK (for ATP-dependent PCK) (35), and Myocbacterium smegmatis PCK (for GTP-dependent PCK) (37) as queries.
α4β4-type enzyme composed of PYCA and PYCB subunits.
GTP-dependent enzyme, unless otherwise indicated.
An accession number was used to refer to the unpublished genome data.
ATP-dependent enzyme.
Unfinished genome.
—, No genome sequence.