Table 1b.

Basal activity (LOF).

Receptor	BW	Mutation	Ref.
MC4R	1.57	I → T	48, 153
MC4R	2.62	I → S,T	19,25,173,184,185
			16,19,25,48,186
MC4R	3.24	I → T	45
MC4R	3.53	T → I	48
MC4R	4.41	R → W	25, 45, 48, 172, 173, 184
MC4R	4.50	W → C	95
MC4R	6.34	A → E	45, 184
MC4R	6.42	G → S	45, 48, 185
MC4R	6.61	C → R	25, 173, 187
MC4R	7.52	I → T	48, 172