Table 4.
Complement assessment of a single female patient during two acute atypical haemolytic uraemic syndrome (aHUS) episodes, in convalescence periods after five (first episode) and 10 (second episode) plasmapheresis (PF) sessions and in remission at the time of the study. The patient recovered without need of a renal transplant and carries pathogenic p.Lys323Glu mutation in CFB 17
| Disease phase | Age (years) | C3b/c (<15·8 )* | C3bBbP (<23·5)* | TCC (<2·2)* |
|---|---|---|---|---|
| First acute episode | 2·5 | 155·17 | 61·58 | 2·88 |
| After 5 PF sessions | 2·5 | 21·57 | 19·87 | 1·3 |
| Second acute episode | 3·5 | 116·16 | 115·49 | 0·74 |
| After 10 PF sessions | 3·5 | 22·82 | 10·82 | 0·67 |
| Remission phase | 21 | 10·33 | 6·00 | 0·46 |
*
Normal concentration range (CAU/ml) defined by this study as mean ± 2 standard deviations of control values (n = 19). Values outside the normal range are indicated in bold type. TCC = terminal complement complex.