Table 1.
Sera studied
| rs number | Observed | Variant | Type | Description | Minor allele frequency | ||
|---|---|---|---|---|---|---|---|
| Minor allele | Number tested | Observed | Expected | ||||
| rs800292 | c/t SNP | Factor H | V62I | t (I) protective | 10 658 | 0·232 | 0·213 |
| rs1061170 | c/t SNP | Factor H | Y402H | c (H) susceptible | 10 551 | 0·383 | 0·42 |
| rs2230199 | c/g SNP | C3 SF | R102G | g (G) susceptible | 10 586 | 0·206 | 0·19 |
| Number with 3 genotypes | 9989 | ||||||
| Genotype C | Homozygous protective at all three loci | 331 | 3·3% | ||||
| Genotype A | Heterozygous at all three loci | 558 | 5·6% | ||||
| Genotype B | Homozygous susceptible at all three loci | 55 | 0·6% | ||||
SNP = single nucleotide polymorphism.