Table 2.
Summary of results
| Genotype C (low-risk homozygotes) | Genotype A (heterozygotes) | Genotype B (high-risk homozygotes) | ||||
|---|---|---|---|---|---|---|
| FI concentration (μg/ml) | Median | 46·00 | 43·00 | 43·00 | Kruskal–Wallis statistic | 2·706 |
| Shown in Fig. 1a | 25% percentile | 40·00 | 40·00 | 34·00 | P = 0·2584 | |
| 75% percentile | 52 | 52 | 52 | |||
| Interquartile range | 12·00 | 12·00 | 18·00 | |||
| C3 concentration (μg/ml) | Median | 1·20 | 0·99 | 0·98 | Kruskal–Wallis statistic | 3·707 |
| Shown in Fig. 1b | 25% percentile | 0·92 | 0·93 | 0·90 | P = 0·1567 | |
| 75% percentile | 1·43 | 1·25 | 1·14 | |||
| Interquartile range | 0·52 | 0·32 | 0·24 | |||
| Reduction by 50 μg/ml FI | Median | 37·2% | 29·1% | 22·9% | Kruskal–Wallis statistic | 19·66 |
| of maximum reading (%) | 25% percentile | 29·6% | 20·3% | 13·4% | P = 0·0001 | |
| 75% percentile | 49·1% | 39·7% | 26·4% | |||
| Interquartile range | 19·5% | 19·4% | 13·0% | |||
| Reduction by 50 μg/ml FI | Median | 53·5% | 44·0% | 28·2% | Kruskal–Wallis statistic | 18·41 |
| of 8 h reading (%) | 25% percentile | 46·4% | 32·6% | 16·9% | P ≤ 0·0001 | |
| 75% percentile | 61·0% | 50·4% | 43·7% | |||
| Interquartile range | 14·6% | 17·8% | 26·8% | |||
Sera activated with zymosan in mg/ethylene glycol tetraacetic acid (EGTA) buffer; 18 sera/group. Each serum is from a different individual. FI = Factor I.