Table 3.
Effects of Factor I and mirococept combinations on iC3b formation and destruction in a normal serum
| Factor I concentration μg/ml | 0 | 0 | 25 | 25 | 50 | 50 | |
|---|---|---|---|---|---|---|---|
| Max | Min | Max | Min | Max | Min | ||
| Mirococept | 0 | 100% | 76% | 99% | 62% | 83% | 42% |
| Concentration | 10 | 65% | 49% | 74% | 51% | 63% | 47% |
| μg/ml | 20 | 63% | 59% | 42% | 42% | 33% | 17% |
| 40 | 47% | 37% | 36% | 25% | 20% | 16% | |
| 80 | 31% | 23% | 16% | 5% | 3% | 0% |
Values expressed as % of maximum value with no additions of Factor I or mirococept. Max = maximum value within first 2 h; min = minimum value whenever it occurs.