Table 1.

Haemodynamic and metabolic variables

Group	HR bpm	AF ml/min.	CF ml/min.	CO ml/min.	AoP mmHg	Glucose uptake μmol/min. per g	Oxygen consumption μmol/min. per g
Control	271 ± 14	43.4 ± 0.8	19.6 ± 0.6	62.9 ± 1.0	177 ± 9	7.6 ± 1.1	40.0 ± 3.9
T1AM (2.5 μM)	231 ± 18	37.3 ± 2.9	19.3 ± 2.4	56.7 ± 0.7	173 ± 7	7.3 ± 0.8	37.4 ± 3.5
T1AM (20 μM)	210 ± 12*	22.7 ± 3.3†	17.7 ± 1.0	40.4 ± 3.3†	158 ± 8	7.2 ± 0.8	37.1 ± 5.8
T1AM (25 μM)	154 ± 16†	13.2 ± 2.2†	14.4 ± 0.8†	27.6 ± 2.4†	127 ± 18*	4.5 ± 1.0	21.2 ± 3.2*

Data represent mean ± S.E.M. of 10–16 hearts per group. Measurements were obtained after 20 min. of perfusion. HF, heart rate; AF, aortic flow; CF, coronary flow; CO, cardiac output and AoP, systolic aortic pressure.

^*P < 0.05

^†P < 0.01 versus control, by Dunnett’s test.