Table 1.
Assessment by quantitative RT-PCR of MSC marker expression by leptomeningeal nestin-positive cells
| Protein | Gene | Leptomeningeal nestin-positive cells/BM-MSC fold change | P |
|---|---|---|---|
| Nestin | Nes | 4.9 | <0.01 |
| Collagen type1a | Col1a1 | 0.58 | <0.01 |
| NG2 | Cspg4 | 0.64 | <0.01 |
| CD34 | Cd34 | 0.2 | <0.01 |
| Hyaluronate binding protein (CD44) | Cd44 | 1.16 | 0.16 |
| Stem cell growth factor receptor kit (C-Kit) | Kit | 3.06 | <0.01 |
| Endoglin (CD105) | Eng | 1.24 | <0.01 |
| Fibroblast growth factor receptor 1 | Fgfr1 | 0.017 | <0.01 |
| Fibroblast growth factor receptor 2 | Fgfr2 | 1.93 | <0.01 |
| Fibroblast growth factor receptor 3 | Fgfr3 | 26.93 | <0.01 |
| Cripto-1 | Tdgf1 | 5.48 | 0.06 |
| Oct4 | Pou5f1 | 9.86 | <0.05 |
| Homeobox transcription factor Nanog | Nanog | 3.34 | <0.05 |