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. 2010 Jan 29;13(9b):3668–3679. doi: 10.1111/j.1582-4934.2009.00661.x

Figure 1.

Figure 1

5-aza-dc up-regulates SHP1 expression in colorectal cancer (CRC) cells. (A) Western blot analysis of 5-aza-dc-induced time-dependent increases in SHP1 in CRC cells, whereas SOCS1 and SOCS3 showed no detectable changes. The data presented are from a representative experiment and detection of GAPDH was used as a loading control. (B) Quantitative real-time PCR analysis of SHP1 and SOCSs in SW1116 cells. Results are expressed as relative expression compared with untreated cells. Each value is the mean ± S.D. of three experiments.