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VSMC (α-SM actin, A–D) and macrophage (mac2, E–H) content of aortic root lesions of ApoE-deficient mice after treatment with COX inhibitors. A, E, controls; B, F indomethacin (8 weeks, 3 mg/kg/day); C, G, rofecoxib (8 weeks, 50 mg/kg/day); densitometric quantitation of D, α-SM actin and H, mac2; n= 12, mean ± S.E.M., *P < 0.05.
