. Author manuscript; available in PMC: 2016 Aug 1.

Published in final edited form as: Am J Kidney Dis. 2015 Mar 12;66(2):231–239. doi: 10.1053/j.ajkd.2015.01.016

Table 4. Association between Baseline Participant Characteristics, Incident Kidney Failure, and Incident ESRD.

	Kidney Failure^a		ESRD^b		P for HR difference^d
	HR^c (95% CI)	P	HR^c (95% CI)	P	P for HR difference^d
Age, per 5-y older	1.29 (1.20-1.40)	<0.001	1.11 (0.97-1.26)	0.1	<0.001
Male sex	1.70 (1.41-2.05)	<0.001	1.40 (1.02-1.93)	0.04	0.08
Black race	1.48 (1.21-1.80)	<0.001	1.92 (1.38-2.67)	<0.001	0.1
Hypertension	2.21 (1.77-2.77)	<0.001	1.81 (1.19-2.74)	0.006	0.3
Diabetes	2.51 (2.06-3.04)	<0.001	3.77 (2.65-5.36)	<0.001	0.01
Prevalent CHD	2.02 (1.62-2.53)	<0.001	2.03 (1.39-2.97)	<0.001	0.7
Albuminuria
<30 mg/g	1.00 (reference)		1.00 (reference)
30-300 mg/g	2.93 (2.31-3.72)	<0.001	5.56 (3.73-8.28)	<0.001	<0.001
>300 mg/g	11.2 (8.55-14.6)	<0.001	29.5 (19.8-44.2)	<0.001	<0.001

HR, hazard ratio; CI, confidence interval; CHD, coronary heart disease; ESRD, end-stage renal disease; USRDS, US Renal Data System

ESRD = identified from USRDS registry (treated kidney failure)

Kidney failure = identified from kidney failure-related International Classification of Diseases, 9^th Revision, Clinical Modification (ICD-9-CM)/ICD-10-CM code from hospitalization or death or USRDS registry (treated or untreated kidney failure)

Adjusted HRs from regression model including all characteristics listed in table.

P for test of difference in HR for kidney failure vs. HR for ESRD for the respective characteristic using seemingly unrelated regression