Table 3.
Proteins significantly up-regulated in PR8-infected ATII cells
| Uniprot ID | Protein Name | Number of Peptides Identified |
Fold Change1 (P-value) |
|---|---|---|---|
| Host Defense | |||
| Q8R2Q8 | Bone marrow stromal antigen 2 | 4 | 25.4 (<0.001) |
| P05533 | Lymphocyte antigen 6A-2/6E-1 | 4 | 4.23 (0.018) |
| Q9R233 | TAP binding protein (Tapasin) | 4 | *(0.001) |
| Q07797 | Galectin-3 binding protein | 3 | 3.51(<0.001) |
| P01897 | MHC Class I alpha chain (H2L) | 3 | *(0.014) |
| Q9CQW9 | Interferon induced transmembrane protein 3 | 2 | *(0.001) |
| P01898 | MHC Class I alpha chain (Q10) | 2 | *(0.014) |
| P14426 | MHC Class I alpha chain (D–K) | 2 | *(0.014) |
| P01887 | β-2 microglobulin | 2 | *(0.001) |
| Q99MB1 | Toll-like receptor 3 (TLR3) | 2 | *(0.014) |
| Cytoskeleton | |||
| Q6IFZ6 | Cytokeratin 1B | 4 | 2.28 (0.049) |
| P26040 | Ezrin | 4 | 1.40 (0.045) |
| Q9Z2K1 | Cytokeratin 16 | 2 | 2.89 (0.013) |
| P08730/Q61414 | Cytokeratin 13 or 15 | 2 | 2.23 (0.006) |
| Protein Synthesis | |||
| P62631 | Eukaryotic translation elongation factor 1 alpha 2 | 2 | 1.33 (0.004) |
| Cellular Metabolism | |||
| Q05769 | Cyclooxygenase-2 | 3 | 2.68 (0.006) |
| Q64467 | Glyceraldehyde-3-phosphate dehydrogenase | 2 | 1.53 (0.044) |
1
Fold change expressed as ratio of signal intensity in PR8-infected/mock
P-value determined by Student’s t-test, or
*
G-test when not detected in mock