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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: J Cell Physiol. 2015 Nov;230(11):2837–2847. doi: 10.1002/jcp.25015

Fig. 4.

Fig. 4

Development of ipsilateral pressure hyperalgesia after facet joint puncture. A. Testing of pressure hyperalgesia on the lower back. Measure of the applied force to the injured lumbar fact joints region to elicit vocalization. N=12 per group. * p<0.05, and **, p<0.01 compared to the sham-operated or naïve group. B. Intramuscular injection of bupivacaine followed by pressure hyperalgesia testing. N=6 per group. * p<0.05 compared to the intramuscular injection of saline on FJ OA animals. C. Activity monitor measurements to assess spontaneous exploratory activity. Frequency of vertical crossings was assessed at 12-week post FJ injury. N=12 per group. * p<0.05 compared to the sham-operated group.