. Author manuscript; available in PMC: 2016 Aug 1.

Published in final edited form as: Osteoarthritis Cartilage. 2015 Apr 14;23(8):1348–1356. doi: 10.1016/j.joca.2015.04.004

Table 3. Absolute and percent 4-year changes (mean with 95% confidence interval) subcutaneous and intermuscular fat, and intermuscular tissue cross-sectional areas, PASE score, body mass index (BMI) and body weight in chronically painful versus painless knees.

	Chronically painful (n=43)		Within group p*	Painless (n=43)		Within group p*	Between p group p^#
	Absolute change	% change	Within group p*	Absolute change	% change	Within group p*	Between p group p^#
SCF	+4.69 (1.50, 7.88)	+8.1 (3.1, 13.2)	0.005	-0.08 (-2.88, 2.72)	0.0 (-4.4, 4.4)	0.95	0.03
SCF%TTC	+1.90 (1.08, 2.72)	+6.4 (3.8, 9.0)	<0.001	+0.27 (-0.52, 1.05)	+1.0 (-1.6, 3.6)	0.49	0.006
IMF	+0.45 (0.00, 0.91)	+4.6 (0.5, 8.8)	0.052	+0.51 (0.07, 0.94)	+5.7 (1.3, 10.2)	0.03	0.86
IMF%TTC	+0.21 (-0.03, 0.46)	+3.8 (-0.5, 8.2)	0.09	+0.36 (0.16, 0.56)	+7.3 (3.2, 11.4)	<0.001	0.32
IMT	+0.52 (0.05, 0.99)	+4.0 (0.9, 7.0)	0.03	+0.02 (-0.37, 0.41)	+0.2 (-2.5, 2.9)	0.92	0.08
PASE	-25.6 (-48.8, -2.32)		0.03	-26.0 (-46.9, -5.01)		0.03	0.98
Body mass index	+0.54 (-0.01, 1.10)	+2.3 (0.1, 4.4)	0.06	-0.01 (-0.52, 0.49)	0.0 (-1.7, 1.7)	0.96	0.13
Body Mass	+1.05 (-0.51, 2.61)	+1.7 (-0.4, 3.8)	0.18	-0.52 (-2.03, 1.00)	-0.4 (-2.1, 1.3)	0.49	0.13

SCF=subcutaneous fat; SCF%TTC=percentage of SCF of the total thigh cross-sectional area; IMF=intermuscular fat; IMF%TTC=percentage of IMF of the total thigh cross-sectional area; IMT=intermuscular tissue; PASE=Physical Activity Scale for the Elderly;

p for change over four years;

paired t-test comparing change in painful with that in painless knees