. Author manuscript; available in PMC: 2016 Aug 1.

Published in final edited form as: J Pediatr. 2015 May 23;167(2):409–415. doi: 10.1016/j.jpeds.2015.04.066

Table 3. Results of serologic and microbiologic tests for histoplasmosis of patients with mediastinal masses, according to final diagnosis.

	Overall (%)	Benign (%)	Malignant (%)	Unadjusted OR (95% CI)	P
Ab CF-Y	45/81^* (56)	45/72 (63)	0/9 (0)	∞	<0.001
Ab CF-M	9/79 (11)	9/70 (13)	0/9 (0)	∞	0.59
ID-M band	34/71 (48)	33/62 (53)	1/9 (11)	9.10 (1.07-77.21)	0.04
ID-H band	10/71 (14)	10/62 (16)	0/9 (0)	∞	0.34
Any positive serology	64/96 (67)	63/87 (72)	1/9 (52)	21.00 (2.49- 176.95)	0.005
Positive urine Ag	2/47 (4)	2/41 (5)	0/6 (0)	∞	1.00
Positive blood Ag	0/32 (0)	0/23 (0)	0/9 (0)	0	1.00
Positive blood culture	0/35 (0)	0/27 (0)	0/7 (0)	0	1.00
Any positive test	66/108 (61)	65/68 (68)	1/12 (8)	23.06 (2.85-186.72)	0.003

no./No.

Data are presented as No. (%)

Abbreviations: Ag, H. capsulatum antigen; Ab CF-M, histoplasma mycelial antibody by complement fixation; Ab CF-Y, histoplasma yeast antibody by complement fixation; ID-M, histoplasma mycelial antibody by immunodiffusion; ID-Y, histoplasma yeast antibody by immunodiffusion