Table 1.
Fancd2–/– Placebo | Fancd2–/– SRT3025 | P | Fancd2+/+ Placebo | Fancd2+/+ SRT3025 | P | |
---|---|---|---|---|---|---|
WBCs, ×103/μL | 6.7 ± 0.5 | 9.0 ± 0.8 | 0.02 | 7.4 ± 0.6 | 10.1 ± 1.0 | 0.03 |
RBCs, ×106/μL | 9.9 ± 0.1 | 10.1 ± 0.1 | 0.24 | 10.0 ± 0.1 | 10.1 ± 0.1 | 0.45 |
Hemoglobin, g/dL | 15.1 ± 0.1 | 15.0 ± 0.1 | 0.52 | 15.0 ± 0.2 | 14.8 ± 0.1 | 0.28 |
Hematocrit, % | 53.6 ± 0.6 | 54.2 ± 0.7 | 0.58 | 54.0 ± 0.7 | 53.6 ± 0.8 | 0.71 |
MCV, fL | 54.7 ± 0.4 | 52.7± 0.5 | <0.01 | 54.0 ± 0.3 | 52.8 ± 0.3 | 0.01 |
Platelets, ×103/μL | 390 ± 12 | 435 ± 17 | 0.04 | 505 ± 22 | 584 ± 23 | 0.02 |
Data were pooled results from multiple mice (14 – 15 mice each group) and presented as mean value ± SEM. WBCs denotes white blood cells; RBCs, red blood cells; MCV, mean corpuscular volume.