Table 1.
Control | FECD | |||
---|---|---|---|---|
Mild | Moderate | Advanced | ||
FECD grade | 0 | 1-2 | 3-4 | 5-6 |
Eyes (subjects) | 71 (38) | 32 (18) | 41 (26) | 35 (25) |
Median age (years, range) | 59 (40-80) | 74 (55-87)** | 63 (44-83) | 67 (42-89)* |
Females (%) | 25 (66) | 13 (76) | 16 (70) | 12 (55) |
Phakic eyes (%) | 64 (90) | 22 (69)* | 30 (73)* | 30 (86) |
CCT, Scheimpflug [μm] | 544 ± 26 | 555 ± 29+ | 571 ± 35*** | 590 ± 43*** |
FECD = Fuchs endothelial corneal dystrophy; CCT = Central corneal thickness. Data are unadjusted mean ± standard deviation unless otherwise indicated.
p < 0.05
p < 0.01
p < 0.001 versus controls (GEE models).
Minimum detectable difference of CCT in mild FECD versus controls is 20 μm.