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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Ophthalmology. 2015 Jun 6;122(8):1645–1652. doi: 10.1016/j.ophtha.2015.05.005

Table 4.

Relationships between high-order aberrations (HOAs) and parameters assessing Fuchs endothelial corneal dystrophy (FECD) severity

Anterior HOAs Posterior HOAs Posterior backscatter Anterior backscatter
CCT r = 0.18; p = 0.19 r = 0.22; p = 0.02 r = 0.44; p = 0.01 r = 0.38; p = 0.08
ECDe r = 0.03; p = 0.68 r = −0.33; p = 0.001 r = −0.60; p < 0.001 r = −0.55; p < 0.001
Anterior backscatter r = 0.01; p = 0.96 r = 0.39; p = 0.001 r = 0.72; p <0.001 -
Posterior backscatter r = 0.13; p = 0.20 r = 0.52; p < 0.001 - -

Pearson correlations are given for effective endothelial cell density data (ECDe, n = 100), central corneal thickness (CCT, n = 179), backscatter (n = 91), and HOAs (n = 178) with significance determined by GEE models (age-adjusted).