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. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Mol Psychiatry. 2015 Jan 27;20(12):1499–1507. doi: 10.1038/mp.2014.192

Figure 3. Pvalb/Gad1 mice show heightened novelty seeking.

Figure 3

In an open field when novel object is placed in the center, Tg animals spend significantly more time in the center (p<0.05) (A) and spend significantly more time investigating the object (p<0.05) (B) than Wt littermate controls. See also Supplemental Material 1 for movie. (C) In social interaction tests, Tg animals showed a heightened preference for the novel mouse over the familiar one compared to Wt, (p<0.05). (D) Baseline investigation of neutral and socially-relevant odors is comparable between the Tg and Wt animals and cannot account for their heightened interest in novel stimuli.