TABLE 4.
Adjusted ORs (95% CIs) for melanoma according to adherence to dietary pattern in age- and phototype-stratified analysis1
| All cases (380 cases/719 controls) |
Men (175 cases/319 controls) |
Women (205 cases/400 controls) |
||||
| OR (95% CI) | P-trend | OR (95% CI) | P-trend | OR (95% CI) | P-trend | |
| Age stratification | ||||||
| HEI-2010 | ||||||
| <50 y | 0.89 (0.76, 1.04) | 0.08 | 0.90 (0.67, 1.21) | 0.37 | 0.85 (0.70, 1.04) | 0.06 |
| ≥50 y | 0.93 (0.82, 1.06) | 0.22 | 0.97 (0.80, 1.17) | 0.47 | 0.93 (0.78, 1.01) | 0.48 |
| DASH | ||||||
| <50 y | 0.86 (0.76, 0.98) | 0.03 | 0.93 (0.71, 1.20) | 0.74 | 0.80 (0.70, 0.93) | 0.01 |
| ≥50 y | 0.93 (0.83, 1.04) | 0.25 | 0.94 (0.80, 1.10) | 0.36 | 0.94 (0.80, 1.11) | 0.65 |
| GMI | ||||||
| <50 y | 0.87 (0.76, 0.99) | 0.04 | 0.82 (0.62, 1.09) | 0.17 | 0.85 (0.73, 1.00) | 0.05 |
| ≥50 y | 1.03 (0.93, 1.14) | 0.58 | 1.02 (0.88, 1.19) | 0.78 | 1.02 (0.88, 1.18) | 0.84 |
| IMI | ||||||
| <50 y | 0.93 (0.83, 1.06) | 0.27 | 1.04 (0.84, 1.30) | 0.71 | 0.83 (0.70, 0.97) | 0.02 |
| ≥50 y | 0.98 (0.89, 1.08) | 0.74 | 0.90 (0.78, 1.04) | 0.14 | 1.08 (0.94, 1.24) | 0.29 |
| Phototype stratification | ||||||
| HEI-2010 | ||||||
| Phototype I-II | 0.90 (0.78, 1.05) | 0.14 | 1.00 (0.78, 1.28) | 0.78 | 0.86 (0.70, 1.06) | 0.16 |
| Phototype III-IV | 0.90 (0.73, 1.11) | 0.33 | 0.83 (0.57, 1.20) | 0.37 | 0.98 (0.75, 1.28) | 0.74 |
| DASH | ||||||
| Phototype I-II | 0.89 (0.78, 1.01) | 0.09 | 0.89 (0.72, 1.08) | 0.27 | 0.90 (0.76, 1.06) | 0.26 |
| Phototype III-IV | 0.93 (0.79, 1.10) | 0.48 | 1.13 (0.85, 1.49) | 0.50 | 0.84 (0.67, 1.06) | 0.20 |
| GMI | ||||||
| Phototype I-II | 0.96 (0.85, 1.09) | 0.53 | 1.00 (0.82, 1.22) | 0.99 | 0.94 (0.80, 1.11) | 0.47 |
| Phototype III-IV | 0.98 (0.83, 1.15) | 0.77 | 0.97 (0.75, 1.25) | 0.79 | 0.97 (0.78, 1.22) | 0.80 |
| IMI | ||||||
| Phototype I-II | 0.90 (0.79, 1.02) | 0.10 | 1.00 (0.83, 1.20) | 1.00 | 0.82 (0.68, 0.98) | 0.03 |
| Phototype III-IV | 1.03 (0.89, 1.20) | 0.68 | 1.02 (0.80, 1.30) | 0.88 | 1.08 (0.88, 1.34) | 0.44 |
Adjusted for age, phototype, BMI, nonalcoholic energy intake, sunburn history, skin sun reaction, and education. OR for melanoma for 10-point increase in HEI-2010, 3-point increase in DASH, and 1-point increase in GMI and IMI pattern scores. DASH, Dietary Approaches to Stop Hypertension; GMI, Greek Mediterranean Index; HEI-2010, Healthy Eating Index 2010; IMI, Italian Mediterranean Index; Phototype I, eyes/hair/skin light, high tendency to burn and never/moderate tan; Phototype II, eyes/hair/skin light, moderate tendency to burn and gradual tan or eyes/hair/skin brown, high tendency to burn and moderate tan; Phototype III, eyes/hair/skin brown, moderate/no tendency to burn and gradual/golden tan; Phototype IV, no tendency to burn and intense tan.