TABLE 2.
Folate, vitamin B-12, and TfR concentrations at 24 wk postpartum in a sample of BAN study mothers who were untreated or given HAART with or without LNS1
| HAART | No HAART | Ratio of HAART to no HAART (95% CI) | |
| Folate, nmol/L | |||
| LNS | 19.1 (17.1, 21.1) | 26.0 (24.2, 27.8) | 0.73*** (0.65, 0.83) |
| No LNS | 16.3 (14.6, 18.0) | 18.7 (17.4, 20.0) | 0.88* (0.77, 0.99) |
| Ratio of LNS to no LNS | 1.17* (1.01, 1.35) | 1.39*** (1.26, 1.54) | |
| Vitamin B-12, pmol/L | |||
| LNS | 286 (257.4, 313.7) | 349 (325.7, 372.2) | 0.82** (0.73, 0.92) |
| No LNS | 310 (278.4, 341.1) | 276 (257.4, 294.1) | 1.12 (0.99, 1.27) |
| Ratio of LNS to no LNS | 0.92 (0.80, 1.06) | 1.27*** (1.15, 1.39) | |
| TfR, mg/L | |||
| LNS | 5.0 (4.6, 5.3) | 4.3 (4.1, 4.6) | 1.14** (1.04, 1.25) |
| No LNS | 5.6 (5.2, 6.0) | 4.4 (4.2, 4.6) | 1.28*** (1.17, 1.40) |
| Ratio of LNS to no LNS | 0.88* (0.79, 0.98) | 0.98 (0.92, 1.06) |
Values are adjusted geometric means (95% CIs) or ratios (95% CIs). Folate and vitamin B-12: no HAART, no LNS, n = 237; no HAART, LNS, n = 238; HAART, no LNS, n = 103; HAART, LNS, n = 110. TfR: no HAART, no LNS, n = 237; no HAART, LNS, n = 238; HAART, no LNS, n = 104; HAART, LNS, n = 111. Models controlled for season, baseline CD4 count, baseline viral load, and use of folate inhibitors (for folate only) and included significant HAART × LNS interactions (folate: P = 0.051; vitamin B-12: P < 0.001; TfR: P = 0.085). *,**,***Significant ratio: *P < 0.05, **P < 0.01, ***P < 0.001. BAN, Breastfeeding, Antiretrovirals, and Nutrition; HAART, highly active antiretroviral therapy; LNS, lipid-based nutrient supplements; TfR, transferrin receptor.