Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Aug;146(2):173–181. doi: 10.1085/jgp.201511422

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Sirrieh et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 6. — Schematic of inhibition. The inhibitors of the NMDA receptor ifenprodil and zinc both induce cleft-closure conformational changes in the GluN2 ATD. Presumably, proton inhibition, which is affected by the binding of ifenprodil or zinc, influences the conformation of the GluN2 ATD as well.