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. 2015 Jul 27;212(8):1153–1169. doi: 10.1084/jem.20142047

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Figure 3. — Distribution of viral antigen and CD11c expression in the persistently infected brain. (A) Representative flow plots show the frequency of microglia containing LCMV antigen in carrier mice versus uninfected naive controls. Microglia were identified as CD45^lo/int Thy1.2⁻ Gr-1⁻ CD11b⁺ cells. Bar graph depicts the mean ± SD, and each dot represents an individual mouse. All data from a total of four independent experiments (n = 2–3 mice per group per experiment) are graphed. The asterisk denotes a statistically significant difference (*, P < 0.001) between the two groups. (B and C) Representative images of sagittal brain sections are shown for CD11c-YFP⁺ (green) carrier mice that are either untreated (B) or received adoptive immunotherapy (day 11; C) seeded with OFP⁺ P14 CD8⁺ T cells (red; n = 3 mice per group). Cell nuclei are shown in blue. Data are representative of three independent experiments.