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. 2015 May 27;17(4):331–337. doi: 10.1007/s40272-015-0136-2
Metoclopramide, the only gastrointestinal motility agent widely used in the USA, has a black-box warning for tardive dyskinesia.
We found that, nonetheless, it is used chronically by at least 28,000 US children, most of whom have at least one health service claim for symptomatic gastroesophageal reflux (GERD).
This suggests a perception that many US children with symptoms suggestive of GERD are not adequately treated by lifestyle changes and acid suppression.