Table 2.
Summarized results of antibody specificity to either full length (206) or BoNT/A-cleaved (197) forms of SNAP25 in individual assays.
| Antibody | Specificity | Western blot | Rat bladder | Rat skin | Human skin | Rat DRG culture |
|---|---|---|---|---|---|---|
| SMI-81R | SNAP25206/197 | 206 + 197 | 206 + 197 | 206 + 197 | n/t | 206 + 197 |
| MC-6050 | SNAP25206/197 | 197 | 197 | 206 + 197 + b | n/t | n/t |
| MC-6053 | SNAP25197 | 197 | 197 | 206 + 197 + b | 206 + 197 | 197 + b |
| Ab632 | SNAP25197 | 197 | 197 | 197 | n/t | 197 |
| Ab635 | SNAP25197 | 197 | 197 | 197 | 197 | n/t |
| RGT-1092 | SNAP25197 | 197 | 206 + 197 | 206 + 197 | n/t | n/t |
n/t = not tested; b = background.