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. 2015 Jul 28;5:12440. doi: 10.1038/srep12440

Figure 5. ACEA-induced neuroprotection against cerebral ischemia/reperfusion injury in mice.

Figure 5

(A) Neurological assessment at 24 h, 48 h and 72 h after reperfusion (n = 13). Data represent the median. (B) Representative photomicrographs of TUNEL staining in hippocampal CA1 region. Scale bars = 50 μm. (C) Quantitative analysis of the number of TUNEL-positive cells in hippocampal CA1 region at 72 h after reperfusion (n = 5). (D) Western blot showing representative the expression of cleaved caspase-3 (Cl. Cas-3) protein in the hippocampus at 72 h after reperfusion (n = 5). Data represent mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001. BCCAO: bilateral common carotid artery occlusion; Hemo: hemopressin.