Table 1.
Effect of ellagic acid on cardiovascular parameters and body weight.
| Parameters | Control | l-NAME | |||
|---|---|---|---|---|---|
| Vehicle | EA (mg/kg/day) | Vehicle | EA (mg/kg/day) | ||
| 15 | 7.5 | 15 | |||
| SBP (mmHg) | 121.9 ± 1.8 | 122.7 ± 2.3 | 199.4 ± 6.1 * | 167.5 ± 3.0 *,# | 164.6 ± 4.9 *,# |
| DBP (mmHg) | 78.3 ± 2.0 | 78.8 ± 2.1 | 140.4 ± 4.0 * | 113.6 ± 3.1 *,# | 111.2 ± 3.7 *,# |
| MAP (mmHg) | 95.4 ± 1.9 | 95.5 ± 2.2 | 164.3 ± 4.6 * | 136.8 ± 3.2 *,# | 133.1 ± 4.2 *,# |
| HR (beat/min) | 357.9 ± 6.0 | 362.5 ± 5.9 | 424.8 ± 6.2 * | 379.4 ± 5.5 *,# | 368.0 ± 3.1 *,# |
| HBF (mL/100 g tissue/min) | 8.3 ± 0.8 | 7.1 ± 0.4 | 4.2 ± 0.3 * | 6.4 ± 0.2 *,# | 6.4 ± 0.3 *,# |
| HVR (mmHg/min/100 g/mL) | 12.1 ± 1.4 | 13.8 ± 0.8 | 39.5 ± 3.5 * | 20.5 ± 1.2 *,# | 20.4 ± 1.2 *,# |
| Body weight (g) | 417.1 ± 4.6 | 418.0 ± 6.0 | 409.5 ± 2.6 | 414.4 ± 4.4 | 410.5 ± 4.3 |
Values are expressed as mean ± SEM, n = 10. * p < 0.05 when compared to control group and # p < 0.05 when compared to vehicle L-NAME group.